Race officials say the dog died of injuries Sunday night caused when a snowmobiler ran into the team of Jennifer Freking of Finland, Minn.
The accident occurred on the Yukon River near Koyukuk. Race Marshall Mark Nordman says a 3-year-old female named Lorne died.
Race officials have no other details. Alaska State Troopers have been notified.
The dog is the second one to have died during this year's race.
A 7-year-old male in the team of rookie musher John Stetson of Duluth, Minn., died of pneumonia. Stetson then scratched from the race.
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