One Alaskan already owns one medal and has a chance to win more, while another faces elimination at the Paralympic Games in London.
Shirley Reilly of Barrow claimed the silver medal in Sunday's 5,000-meter wheelchair race, missing gold by .04 of a second.
She is entered in several other races, including her specialty -- the marathon, which will be contested on the final day of competition Sunday. Reilly, the winner of this year's wheelchair divisions at the Boston Marathon, is among the favorites.
While Reilly is aiming for more hardware, East High graduate Keith Johnson and his U.S. teammates are fighting for survival in the 7-a-side men's soccer tournament.
Johnson, 32, is the goalkeeper for the Americans, who are 0-2 in pool play with one match remaining. The U.S. will try to rebound from a pair of bruising losses -- 9-0 to Ukraine and 8-0 to Brazil -- on Wednesday when it meets Great Britain. Johnson was in net both matches and has stopped 30 shots.
The top two teams from each pool advance to Friday's semifinals.
Reilly, 27, won silver on Sunday when Switzerland's Edith Wolf edged her at the finish line. Wolf won in 12 minutes, 27.87 seconds; Reilly was right behind in 12:27.91.
It was Reilly's first medal in three appearances at the Paralympics. She competed in Athens in 2004 and Beijing in 2008.
Reilly was born three weeks premature and was paralyzed from the waist down, according to her Paralympics biography. When she was 3, she underwent the first of three surgeries that fused rods to her spine to stabilize it, procedures that took her out of Alaska.
She lives in Tucson, where she goes to college and trains with the University of Arizona Wheelchair Track and Road Racing Team.
Johnson, who graduated from East in 1999, is making his second Paralympics appearance and the first since he played in goal for the United States at the 2004 games in Athens.
He was born with cerebral palsy, a non-progressive motor disorder that affects body movement. After the 2004 Paralympics he moved from Anchorage to Houston, Texas.